A New Article published from the Dental Trauma Guide Research Group
Josephine S. Henriksen1 | Eva Lauridsen2 | Simon S. Jensen2,3 | Thomas A. Gerds4 & Nuno V. Hermann1
Abstract
Purpose: The aim of this study was to investigate the potential for pulp revascularization in relation to patient age at the time
of injury following luxation injury of mature anterior permanent teeth.
Materials and methods: A total of 93 teeth from 70 patients were included. The patients were divided into subgroups based
on their age at the time of the injury. Statistics: the Aalen–Johansen method was used to estimate the risks of pulp canal
obliteration (PCO) and pulp necrosis (PN). The absolute 2 year risks of PCO and PN were obtained with cause-specific Cox
regression and reported separately for each cohort, standardised to age at injury and degree of repositioning
Results: For the group younger than 15 years of age, the risk of PN after 12 months was 62.3% [95% CI 44.9; 79.7] in the
cohort from 1972 to 1980 and 28.6% [95% CI 4.9; 52.2] in the cohort from 2012 to 2020. For the age group 16–20 years, the
risk of PN after 12 months was 66.7 [95% CI 40.0;93.3] in the cohort from 1972 to 1980 and 25% [95% CI 0.0;55.0] in the
cohort from 2012 to 2020. For the age group between 21 and 25, the risk of PN after 12 months was 66.7% [95% CI 40.0;
93.3] in the cohort from 1972 to 1980 and 55.6% [95% CI 23.1; 88.0] in the cohort from 2012 to 2020.
Conclusion: There is potential for pulp revascularization in mature anterior teeth with lateral luxation in patients up to 25
years of age. The risk of PN appears to increase with age.
Keywords: Pulp revascularization · Pulp necrosis · Lateral luxation · Dental traumatic injury 
1 Department of Pediatric Dentistry and Clinical Genetics,
School of Dentistry, Faculty of Health Sciences, University
of Copenhagen, Copenhagen, Denmark
2 Department of Oral and Maxillofacial Surgery, Copenhagen
University Hospital, Rigshospitalet, Copenhagen, Denmark
3 Department of Oral Surgery, Research Section for Oral
Biology and Immunopathology, School of Dentistry, Faculty
of Health Sciences, University of Copenhagen, Copenhagen,
Denmark
4 Department of Biostatistics, Faculty of Health Sciences,
University of Copenhagen, Copenhagen, Denmark